Basic information regarding the diagnosis, clinical manifestations, and management of the main diseases encountered in clinical practice are drawn from the 18th edition of Harrison's Internal Medicine. These are presented succinctly but comprehensively in the color Companion Handbook of Internal Medicine. This edition covers every field of clinical medicine, including the following:
- Etiology and epidemiology
- Clinical pathophysiology
- Signs and symptoms
- Differential diagnosis
- Clinical and laboratory findings
- Therapeutic approach
- Practice guidelines