Continuing the great tradition of Western Philosophy in its adventure around Being and Essence, this study explores the dimension that the concept of Heideggerian "ontological Difference" takes on the threshold of the 21st century, distilled through its conception as "Difference" in postmodernity and the discourse of the Unconscious in the classical and poststructuralist psychoanalytic example. By traversing the philosophical reflection of fundamental ontology through the insights of poststructuralism and psychoanalysis, which knows the castration of Gender, not that of Death, and by ontologically grounding the meaning that has been ethically determined only until now as that of the Unconscious, this research accomplishes the Passage to the post-deconstructive Paradigm of Thought that follows the postmodern, opening up psychoanalysis, art, science, and philosophy to the New Age. Thus clarifying Being in its New Face as "Vehicle/Wound" upon the "Pain of Experience" within the framework of the deconstructive reading of the hitherto unpublished Heidegger, but also of René Descartes himself as the precursor of the Subject, it persists in the "Pain of Arch-Castration" as decisive for the New Thought without escaping it as psychoanalysis and poststructuralism have done until now through the "Difference" or the "Pleasure-Pain", re-signifying ontologically Death, the condition of arch-possibility of the Cut into the Other and Gender, as it precedes the traditional from Being to its final Explosion upon the New Subject. The post-postmodern. The Transgendered Last God, in the likeness of the Neo-Human, who in his ontologically Infinite opens up to the Cogito of Love. Inaugurating an ontoethical Revolution. New Culture of Death.